Plavix May Cause Cerebral, Gastrointestinal Bleeding

Are you a Plavix user who has suffered from cerebral bleeding, gastrointestinal bleeding, or from other internal hemorrhaging, such as bleeding ulcers? Plavix, the popular blood thinner drug could be to blame. Recent studies indicate that Plavix patients are more likely to experience gastrointestinal bleeding and other bleeding than what was previously thought. Our Plavix lawyers want to hear from anyone who suffered from this drug side effect.

Victims of this blood thinner may be eligible to file a Plavix lawsuit.  Plavix lawyers at our personal injury firm who specialize in defective drug litigation are offering free lawsuit evaluations to victims of Plavix side effects, such as internal hemorraging, thrombotic thrombocytepenic purpura (TTP), and heart attack. We urge you to contact one of our Plavix attorneys today to protect your legal rights.

Plavix Issues

For years, it was thought the Plavix would cause less gastrointestinal bleeding, cerebral bleeding, and other internal hemorraging than an alternative blood thinner, Warfarin. But recently, a study conducted by the U.S. Centers for Disease Control and published in the Archives of Internal Medicine found the risk of internal hemorrhaging among Plavix-aspirin patients was significantly higher than thought.

While the CDC study did find that Warfarin was associated with a higher rate of bleeding than the Plavix-aspirin combo, the combination therapy did not do as well in that area as was expected. For both regimens, the number of hospital admissions because of bleeding was similar. And bleeding-related visits to emergency department visits, such as for bleeding ulcers, and cerebral bleeding, were only 50 percent lower for those on the Plavix-aspirin combination prescription.

Another study in the New England Journal of Medicine found that patients taking Plavix are 12 times more likely to suffer recurrent bleeding ulcers, including cerebral bleeding and Plavix gastrointestinal bleeding than those who received a combination of aspirin and a heartburn pill.

Heartburn drugs like Prilosec, Nexium, Prevacid, Aciphex, and Protonix are often prescribed to reduce the risk of gastrointestinal bleeding from the Plavix-aspirin combo. But now, it appears that Plavix users can’t even count on those drugs to reduce the risk of Plavix gastrointestinal bleeding, from bleeding ulcers and so on. In November 2009, the U.S. Food & Drug Administration (FDA) warned that Prilosec could impede the body’s production of the liver enzyme CYP2C19. This enzyme is needed to convert Plavix to its active form.

It was already known that people who have reduced functioning of their CYP2C19 liver enzyme are unable to convert Plavix to its active form. Because Prilosec inhibits CYP2C19, it may impact the effectiveness of Prilosec. The FDA said it was unknown if other heartburn drugs in the same class as Prilosec, known as Proton Pump Inhibitors, might interfere with Plavix, but advised patients not to take Nexium (esomeprazole), Tagamet and Tagamet HB (cimetidine), Diflucan (fluconazole), Nizoral (ketoconazole), VFEND (voriconazole), Intelence (etravirine), Felbatol (felbamate), Prozac, Serafem, Symbyax (fluoxetine), Luvox (fluvoxamine) and Ticlid (ticlopidine).

Legal Help for Victims of Plavix

Parker Waichman LLP is one of the preeminent personal injury law firms in the U.S. Parker Waichman LLP is listed in Best Lawyers, the oldest and most respected peer-review publication in the legal profession. The attorneys of Parker Waichman LLP are also the authors of “Personal Injury Law for Dummies,” an easy to understand guide to all aspects of personal injury law.

If you or a loved one suffered from Plavix side effects, such as gastrointestinal bleeding, cerebral bleeding, other internal hemarraging, bone marrow damage, heart attack, stroke or were diagnosed with thrombotic thrombocytepenic purpura (TTP),  you may be entitled to receive compensation for medical bills, lost wages, pain and suffering, and other damages. For a free legal consultation with one of our Plavix attorneys, please fill out our online form or call 1-800 LAW INFO (1-800-529-4636) today.